1.
Journal of Korean Medical Science
;
: S16-S16, 2000.
Article
in English
| WPRIM
| ID: wpr-117537
ABSTRACT
No abstract available.
Subject(s)
Animals , Bicarbonates/metabolism , Biological Transport/physiology , Pancreatic Ducts/metabolism , Perfusion
2.
Journal of Korean Medical Science
;
: S27-S28, 2000.
Article
in English
| WPRIM
| ID: wpr-117533
ABSTRACT
1. 5-HT inhibits spontaneous fluid secretion as well as stimulated secretion with secretin (cAMP mediated) or ACh (Ca2+ mediated) in the isolated guinea pig pancreatic ducts. 2. The inhibitory effect of 5-HT is reversible and is dependent on the concentration in the range 0.01-0.1 microM, which is much lower than those that affect intestinal motility and secretion. 3. The 5-HT3 receptor in duct cells appears to mediate the inhibitory effect of 5-HT. 4. [Ca2+]i is unlikely to mediate the inhibitory effect of 5-HT.